Signac is a comprehensive R package for the analysis of single-cell chromatin data.
Signac is designed for the analysis of single-cell chromatin data, including scATAC-seq, single-cell targeted tagmentation methods such as scCUT&Tag and scNTT-seq, and multimodal datasets that jointly measure chromatin state alongside other modalities.
Signac currently supports the following features:
Check out the Signac vignettes page for in-depth tutorials.
For full installation instructions see the install page.
If you encounter a bug or have a feature request, please open an issue.
If you would like to discuss questions related to single-cell analysis, you can open a discussion.
Signac runs on a quarterly release schedule. Additional releases will be scheduled in the case of urgent bug fixes. The development roadmap can be viewed on GitHub here.