Signac: Analysis of Single-Cell Chromatin Data

A framework for the analysis and exploration of single-cell chromatin data. The 'Signac' package contains functions for quantifying single-cell chromatin data, computing per-cell quality control metrics, dimension reduction and normalization, visualization, and DNA sequence motif analysis. Reference: Stuart et al. (2021) doi:10.1038/s41592-021-01282-5 .

See also

Useful links:

• https://github.com/stuart-lab/signac

• https://stuartlab.org/signac

• Report bugs at https://github.com/stuart-lab/signac/issues

Author

Maintainer: Tim Stuart stuartt@gis.a-star.edu.sg (ORCID)

Authors:

• Avi Srivastava asrivastava@nygenome.org (ORCID)

Other contributors:

• Paul Hoffman phoffman@nygenome.org (ORCID) [contributor]

• Rahul Satija rsatija@nygenome.org (ORCID) [contributor]